Beta-blockers for atrial fibrillation: must we consider asymptomatic arrhythmias?

beta-blockers for atrial fibrillation: must we consider asymptomatic arrhythmias?

Atrial fibrillation (AF) affects more than 5% of the U.S. population .65 years, and 10% of those .80 years of age, making it the most common arrhythmia requiring treatment. Efforts to treat with ablation or devices show promise, but to date, pharmacologic therapy represents the mainstay of AF treatment. The benefit of efforts to control the rhythm (as opposed to rate control with anticoagulatio...

Combined treatment of atrial fibrillation with quinidine and beta-blockers.

Atrial Fibrillation and Ventricular Arrhythmias

Circulation. 2017;135:593–608. DOI: 10.1161/CIRCULATIONAHA.116.025312 February 7, 2017 593 Anne M. Gillis, MD ABSRACT: Sex-specific differences in the epidemiology, pathophysiology, clinical presentation, clinical treatment, and clinical outcomes of atrial fibrillation (AF), sustained ventricular arrhythmias, and sudden cardiac death are recognized. Sex hormones cause differences in cardiac ele...

Calcium channel blockers and beta-blockers versus beta-blockers alone for preventing exercise-induced arrhythmias in catecholaminergic polymorphic ventricular tachycardia.

BACKGROUND The mainstay of therapy for catecholaminergic polymorphic ventricular tachycardia (CPVT) is maximal doses of beta-blockers. However, although beta-blockers prevent exercise-induced ventricular tachycardia (VT), most patients continue to have ventricular ectopy during exercise, and some studies report high mortality rates despite beta-blockade. OBJECTIVE The purpose of this study wa...

Asymptomatic arrhythmias in patients with symptomatic paroxysmal atrial fibrillation and paroxysmal supraventricular tachycardia.

BACKGROUND Paroxysmal atrial fibrillation and paroxysmal supraventricular tachycardia are recognized clinically when patients seek treatment for symptoms due to recurrent arrhythmias; atrial fibrillation also increases the risk of stroke. The frequency with which asymptomatic arrhythmias occur in patients with these arrhythmias is unknown. METHODS AND RESULTS Twenty-two patients with paroxysm...